Meta-analysis links Sodium and CVD mortality in general population

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A meta-analysis of 11 studies with a total of 228,785 participants is the most recent of its kind to link higher sodium (Na) intake with higher CVD mortality. A meta-regression analysis showed that for every increase of 10 mmol/d in Na intake, CVD mortality increased significantly by 1 % (P = 0.016). The study also did not find a ‘J-shaped’ curve in the relationship between Na intake and CVD mortality in the general population, as with some other recent studies, because it excluded studies of people with diseases, where reverse causality is likely to produce a J- or U- shaped result.

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